|
KMID : 1161220230660010028
|
|
Clinical and Experimental Pediatrics
2023 Volume.66 No. 1 p.28 ~ p.31
|
|
|
Not breastfeeding and risk of autism spectrum disorders among children: a meta-analysis
|
|
Jenabi Ensiyeh
Bashirian Saeid
Salehi Amir Mohammad
Khazaei Salman
|
|
|
Abstract
|
|
|
Background: To our knowledge, this is the first meta-analysis of the association of not breastfeeding and the risk of autism spectrum disorder (ASD) based on observational studies.
Purpose: This meta-analysis aimed to evaluate of the association of not breastfeeding and the risk of ASD.
Methods: Three databases (PubMed, Web of Science, and Scopus) were systematically searched until December 2021. Heterogeneity was determined using the chi-square test and its quantity was measured using the I2 statistic. The Begg line regression test was used to assess publication bias. A random-effects model was used to analyze the data. Seven studies were included in this meta-analysis.
Results: The total study population included 3,270 individuals. According to the random-effects model, the estimated odds ratio of the risk of ASD associated with not breastfeeding was 1.81 (95% confidence interval, 1.35?2.27; I2=0%).
Conclusion: The results of the included studies were homogeneous. Our findings showed that not breastfeeding is a risk factor for ASD. These results suggest the importance of breastfeeding in decreasing the risk of ASD in children.
|
|
|
KEYWORD
|
|
|
Autism spectrum disorders, Breastfeeding, Child, Meta-analysis
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|